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Praxair's ControLyo™ nucleation on-demand technology can deliver improved product uniformity, quality and yield while reducing cycle times by up to 40%. Until now, the freezing step of lyophilization was uncontrolled due to the random nature of the nucleation process. Praxair's breakthrough, proprietary technology makes nucleation control within 1°C of its freezing point a reality. Requiring only a simple retrofit to your lyophilization equipment - no changes to existing drug formulations needed.

Highlights include:
  • Improved product quality
  • Increased lyophilization capacity
  • Improved product yield
  • Provides predictable process scale-up and transfer
To learn more and see sample vials uniformly nucleate, watch our video.

ControLyo™ Technology
Demo Video »
For more information, request the ControLyo Technology Spec Sheet.
Or email a Praxair representative directly at Ranko_Bursac@praxair.com.

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Request Technical Paper
ControLyo™ Technology Spec Sheet

Increasing Lyophilization Productivity, Flexibility and Reliability Using Liquid Nitrogen Refrigeration Technical Article

Praxair DCOOL™ and NCOOL™ Systems Technical Paper










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